![]() ![]() ![]() Origin and evolution of the self- organizing cytoskeleton in the network of eukaryotic organelles. However, it should be recognized that the concept of “master†and “servant†cell components is a metaphor in present-day living organisms their organellar components are considered to be interdependent and inseparable. Our proposal is that maternal mitochondria are the selfish “master†entities of the eukaryotic cell with respect not only to their propagation from cell-to-cell and from generation-to-generation but also to their regulation of all other cellular functions. Thus, it is proposed that the “selfish gene†hypothesis of Dawkins1 is not the only possible perspective for comprehending genomic and cellular evolution. The present paper discusses how the endosymbiotic theory implicates a new hypothesis about the hierarchical and communicational organization of the integrated prokaryotic components of the eukaryotic cell and provides a new angle from which to consider the theory of evolution and its bearing upon cellular complexity. This new perspective on the organization of the cell has been further expanded to reveal the concept of a public milieu, the cytosol, in which Energides and mitochondria live, each with their own private internal milieu. ![]() ![]() Mitochondria represent one of these types of previously independent organisms, the Energide, is another type. Some of these units were originally free-living prokaryotes, which were engulfed during evolutionary time. The Energide concept, as well as the endosymbiotic theory of eukaryotic cell organization and evolution, proposes that present-day cells of eukaryotic organisms are mosaics of specialized and cooperating units, or organelles. Are maternal mitochondria the selfish entities that are masters of the cells of eukaryotic multicellular organisms?īarlow, Peter W Baldelli, E BaluÅ¡ka, Frantisek ![]()
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